IGF-1 LR3 1mg – Extended Half-Life Insulin-Like Growth Factor Research Support
 
IGF-1 LR3 (Long Arginine 3-Insulin-like Growth Factor-1) is a high-purity, synthetic analog of naturally occurring IGF-1. It is a 83-amino acid polypeptide that includes a substitution of Arginine for Glutamic Acid at position 3, as well as a 13-amino acid extension peptide at the N-terminus. It is synthesized for advanced laboratory research focusing on cellular proliferation, myogenesis, and the biochemical pathways of tissue growth.
 
IGF-1 LR3 is extensively studied in experimental models for its significantly increased potency and extended half-life compared to standard IGF-1. Researchers investigate its unique molecular structure, which prevents it from binding to insulin-like growth factor-binding proteins (IGFBPs). This lack of binding results in higher bioavailability and a prolonged duration of action—up to 20-30 hours—allowing for sustained study of its anabolic effects. In laboratory settings, it is researched for its ability to stimulate muscle cell hyperplasia (the creation of new muscle cells) and facilitate the transport of glucose and amino acids into cellular structures. Its biochemical mechanism involves the activation of the PI3K-Akt signaling pathway, making it a primary subject for studies involving skeletal muscle regeneration, bone density maintenance, and cellular repair.
 
This advanced research-grade peptide is frequently utilized in laboratory settings to analyze the interaction between growth factor signaling and protein synthesis, as well as the maintenance of cellular resilience during physiological challenges.
High purity: 99% HPLC
CAS#: 946870-92-4
Molecular Weight: 9117.5 g/mol
Chemical Formula: $C_{400}H_{625}N_{111}O_{115}S_{9}$
 
For laboratory research use only. Not for human or veterinary consumption.
 
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.